Progesterone Impurity 52 CAS 14508-05-5
| CAS No. | 14508-05-5 |
| Molecular Formula | C22H32O3 |
| Molecular Weight | 344.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Progesterone Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Progesterone Impurity 52 (CAS 14508-05-5, C22H32O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H32O3, Progesterone Impurity 52 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 344.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H32O3 |
| Molecular Weight | 344.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Progesterone Standards
- Progesterone Impurity N3 (CAS 5327-60-6)
- Progesterone Impurity 46 (CAS CATO-C4X-150246)
- Progesterone Impurity 65 (CAS CATO-C4X-150265)
- Progesterone Impurity 69 (CAS CATO-C4X-150269)
- Progesterone Impurity 81 (CAS CATO-C4X-150281)
- Progesterone Impurity 85 (CAS 151122-70-2)
- Progesterone Impurity N38 (CAS 70081-51-5)
- Progesterone Impurity 62 (CAS 87421-42-9)
Recommended Standards
- Medroxyprogesterone Acetate EP Impurity I (CAS CATO-C4X-14573)
- Spironolactone Impurity 19 (CAS CATO-C4X-134519)
- Dutasteride EP Impurity B (CAS 2512195-98-9)
- 1,3-Dioctanoyl Glycerol (CAS 1429-66-9)
- Lesinurad impurity 16 (CAS CATO-C4X-147816)
- Dapagliflozin Impurity 50 (CAS CATO-C4X-113850)
- Phenylephrine Impurity 64 (CAS CATO-C4X-146764)
- N-(2-(thiophen-3-yl)benzyl)ethanamine (CAS 1495412-69-5)
- 1,5-Dioxaspiro[5.5]undecan-9-ol (CAS 76626-10-3)
- 6,6-Difluoro-2-azabicyclo[3.1.0]Hexane hydrochloride (CAS 2306261-77-6)
- 3-((3-Fluorobenzyl)thio)-6-(4-methoxyphenyl)pyridazine (CAS 921164-16-1)
- 3-(Prop-2-yn-1-ylamino)pyrazine-2-carboxylic acid (CAS 1249947-85-0)
- 2-Amino-2-(4-(dimethylamino)phenyl)acetic acid (CAS 29884-03-5)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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