Sofosbuvir Impurity 114 CAS 701-64-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.701-64-4
Molecular FormulaC6H7O4P
Molecular Weight174.09 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Sofosbuvir Impurity 114 CAS 701-64-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Sofosbuvir Impurity 114 (CAS 701-64-4) is a certified pharmaceutical impurity reference standard with the molecular formula C6H7O4P and a molecular weight of 174.09 g/mol.

Owing to a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, Sofosbuvir Impurity 114 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC6H7O4P
Molecular Weight174.09 g/mol
Purity>95%
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957

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