Levocetirizine Impurity 55 CAS 705289-61-8
| CAS No. | 705289-61-8 |
| Molecular Formula | C19H23ClN2O |
| Molecular Weight | 330.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Levocetirizine Impurity 55 (CAS 705289-61-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H23ClN2O and a molecular weight of 330.85 g/mol.
The molecular framework of Levocetirizine Impurity 55 (C19H23ClN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H23ClN2O |
| Molecular Weight | 330.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levocetirizine Standards
- Levocetirizine Impurity 5 (CAS 109036-15-9)
- Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine) (CAS 300543-56-0)
- Levocetirizine Impurity 66 (CAS 439858-21-6)
- Levocetirizine Impurity 68 (CAS CATO-C4X-108368)
- Levocetirizine Impurity 35 (CAS 130018-76-7)
- Levocetirizine Impurity 80 (CAS 1232460-31-9)
- Levocetirizine Impurity 42 (CAS CATO-C4X-108342)
- Levocetirizine Impurity 8 (CAS 83881-46-3)
Recommended Standards
- Cetirizine EP Impurity G (CAS 109806-71-5)
- Atropine Impurity 55 (CAS CATO-C4X-148955)
- N-(4-(tert-butyl)thiazol-2-yl)-3-chlorobenzenesulfonamide (CAS 866150-36-9)
- Cetirizine Impurity 26 (CAS CATO-C4X-158226)
- Ibuprofen impurity 125 (CAS CATO-C4X-1082125)
- Atropine Impurity 50 (CAS CATO-C4X-148950)
- Lornoxicam impurity 66 (CAS CATO-C4X-201666)
- 1-(2,4-Dimethylphenoxy)-3-(3,5-dimethylpiperidin-1-yl)propan-2-ol hydrochloride (CAS 473266-93-2)
- 5-Benzo[b]thiophen-3-ylmethylene-3-methyl-2-morpholin-4-yl-3,5-dihydro-imidazol-4-one (CAS 1312024-79-5)
- 2-Amino-3-hydroxy-15-methyl-hexadecanoic Acid Ethyl Ester (CAS 750560-88-4)
- Etoposide impurity 20 (CAS CATO-C4X-202420)
- Ethyl 2-bromo-5-cyano-3-iodobenzoate (CAS 1807162-51-1)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)propanamide (CAS 339010-62-7)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com