Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine) CAS 300543-56-0
| CAS No. | 300543-56-0 |
| Molecular Formula | C17H19ClN2 |
| Molecular Weight | 286.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine) (CAS 300543-56-0, C17H19ClN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Levocetirizine Impurity 1 (Chlorobenzhydryl piperazine) (C17H19ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2 |
| Molecular Weight | 286.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levocetirizine Standards
- Levocetirizine Impurity 5 (CAS 109036-15-9)
- Levocetirizine Impurity 66 (CAS 439858-21-6)
- Levocetirizine Impurity 10 (N-Benzyl-2-[2-[(2-hydroxyethyl)amino]ethoxy]acetamide) (CAS 1391053-09-0)
- Levocetirizine Impurity 55 (CAS 705289-61-8)
- Levocetirizine Impurity 11 (CAS 163837-57-8)
- Levocetirizine Impurity 68 (CAS CATO-C4X-108368)
- Levocetirizine Impurity 35 (CAS 130018-76-7)
- Levocetirizine Impurity 80 (CAS 1232460-31-9)
Recommended Standards
- tert-Butyl 2-(3-chloropropyl)-2-cyanopiperidine-1-carboxylate (CAS 960294-17-1)
- Cetirizine EP Impurity A (CAS 303-26-4)
- rac erythro-3-(5-Amino-6-chloropyrimidin-4-ylamino)-nonan-2-ol (CAS 75166-65-3)
- N,N-Didemethylchlorimipramine (CAS 62724-32-7)
- Azilsartan Impurity 9 (CAS 136285-69-3)
- Dobutamine Impurity 6 (CAS 67952-38-9)
- Bempedoic Acid Impurity 18 (CAS CATO-C4X-218918)
- 2-(Difluoromethyl)-5-iodo-6-methylpyridine-3-carboxylic acid (CAS 1805509-99-2)
- 2-(4,6-Diamino-2-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1806807-30-6)
- 3-Chloro-4-cyano-5-(trifluoromethyl)picolinic acid (CAS 1221791-55-4)
- 5-Bromo-2-(phenethyloxy)aniline (CAS 946699-90-7)
- 4-(3-Pyridyloxy)benzaldehyde (CAS 87626-41-3)
- (-)-4-Methyltartranilic acid (CAS 206761-78-6)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com