Keto Diclofenac Sodium Salt CAS 70757-34-5
| CAS No. | 70757-34-5 |
| Molecular Formula | C14H8Cl2NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.11 g/mol gives Keto Diclofenac Sodium Salt distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Keto Diclofenac Sodium Salt (CAS 70757-34-5, C14H8Cl2NO3Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Keto Diclofenac Sodium Salt (C14H8Cl2NO3Na) contains a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.5, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 332.11 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2NO3 Na |
| Molecular Weight | 332.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Keto Standards
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Recommended Standards
- Rimegepant Impurity 47 (CAS CATO-C4X-248747)
- Clomipramine Impurity 9 (CAS CATO-C4X-12659)
- S-Adenosyl-L-Methionine Impurity 18 (CAS 37063-35-7)
- 2-(6-methyloxan-2-yl)acetonitrile (CAS 343868-07-5)
- 2-Chloro-2-(3,4-dimethoxyphenyl)acetonitrile (CAS 28750-77-8)
- 2-(2,5-Dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic acid (CAS 340309-41-3)
- 6-Bromo-5-(difluoromethyl)-4-nitropyridin-3-ol (CAS 1806072-65-0)
- 5-Amino-4-methylpyridin-3-ol (CAS 1402672-81-4)
- 3-Ethynyl-3-fluoropyrrolidine (CAS 1565079-79-9)
- C-Peptide (human) (CAS 33017-11-7)
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