Naloxone EP Impurity G CAS 70866-64-7
| CAS No. | 70866-64-7 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Naloxone EP Impurity G is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Naloxone EP Impurity G (CAS 70866-64-7), a pharmacopoeial impurity reference standard (molecular formula C20H23NO4, MW 341.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Naloxone EP Impurity G (C20H23NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Naloxone EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related Naloxone Standards
- Naloxone Impurity 18 (CAS CATO-C4X-149318)
- Naloxone Impurity 23 (CAS CATO-C4X-149323)
- Naloxone Hydrochloride EP Impurity C (CAS 2139253-68-0)
- Naloxone Hydrochloride EP Impurity F (CAS 2139253-69-1)
- Naloxone Impurity 17 (CAS CATO-C4X-149317)
- Naloxone-d5 3-Methyl Ether (1.0mg/ml in Acetonitrile) (CAS 1261082-21-6)
- Naloxone-D5 (CAS 1261079-38-2)
- Naloxone Impurity 19 (CAS CATO-C4X-149319)
Recommended Standards
- LCZ-696 Impurity 80 (CAS 128779-47-5)
- Nimesulide EP Impurity E (CAS 905858-63-1)
- Oseltamivir impurity 205 (CAS CATO-C4X-1720205)
- Naltrexone impurity 49 (CAS CATO-C4X-147549)
- Brivaracetam Impurity 192 (CAS CATO-C4X-2007192)
- Pretomanid Impurity 28 (CAS 2512206-85-6)
- Bortezomib Impurity 6 (CAS 1132709-14-8)
- 2-(4-Chlorophenyl)imidazo[1,2-a]pyridine (CAS 38922-74-6)
- 8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin (CAS 93078-83-2)
- 1-(3-(4-Chlorophenyl)-5-methylisoxazol-4-yl)ethan-1-one (CAS 169814-48-6)
- Terbium(III) oxide (CAS 12036-41-8)
- (S)-Cyclooct-2-en-1-ol (CAS 112018-78-7)
- 2-(2,6-Dimethylphenyl)pyrrole (CAS 959738-69-3)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com