Naltrexone impurity 49 CAS CATO-C4X-147549
| CAS No. | CATO-C4X-147549 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Naltrexone impurity 49 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Naltrexone impurity 49 (CAS CATO-C4X-147549), a pharmacopoeial impurity reference standard (molecular formula C20H23NO4, MW 341.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Naltrexone impurity 49 (C20H23NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Naltrexone impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Naltrexone Standards
- Naltrexone Impurity 26 (CAS CATO-C4X-147526)
- Naltrexone EP Impurity C (CAS 189016-90-8)
- Naltrexone (CAS 16590-41-3)
- Naltrexone Impurity 11 (CAS 123086-68-0)
- Naltrexone Impurity 20 (CAS CATO-C4X-147520)
- Naltrexone impurity 31 (CAS 20410-98-4)
- Naltrexone EP Impurity H (CAS 503090-99-1)
- Naltrexone-D3 (CAS 1261080-26-5)
Recommended Standards
- Nimesulide EP Impurity E (CAS 905858-63-1)
- Naloxone Impurity 18 (CAS CATO-C4X-149318)
- Nalmefene Impurity 22 (CAS CATO-C4X-126822)
- Naloxone EP Impurity G (CAS 70866-64-7)
- Posaconazole impurity 242 (CAS CATO-C4X-1208242)
- Cefpirome Impurity 49 (CAS CATO-C4X-120749)
- Demeclocycline Impurity 10 (CAS CATO-C4X-160810)
- 5-(3-Fluoro-4-(methylsulfonyl)phenyl)-4-methylthiazol-2-amine (CAS 593959-27-4)
- 6-Fluoro-1-isopropyl-1H-indole-3-carbaldehyde (CAS 887685-49-6)
- (S)-Methyl 2-((tert-butoxycarbonyl)amino)-4-(methylsulfonyl)butanoate (CAS 160141-86-6)
- 6,6-Dimethylcyclohex-1-en-1-yl trifluoromethanesulfonate (CAS 32363-23-8)
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