Moxifloxacin EP Impurity H CAS 721970-35-0
| CAS No. | 721970-35-0 |
| Molecular Formula | C22H26FN3O4 |
| Molecular Weight | 415.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Moxifloxacin EP Impurity H is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Moxifloxacin EP Impurity H (CAS 721970-35-0, C22H26FN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H26FN3O4, Moxifloxacin EP Impurity H contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O4 |
| Molecular Weight | 415.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Moxifloxacin Standards
- Moxifloxacin EP Impurity F (CAS 721970-37-2)
- Moxifloxacin Hydrochloride EP Impurity C (CAS 1029364-75-7)
- Moxifloxacin impurity 185 (CAS CATO-C4X-1074185)
- Moxifloxacin Impurity 192 (CAS CATO-C4X-1074192)
- Moxifloxacin Impurity 193 (CAS CATO-C4X-1074193)
- Moxifloxacin impurity 195 (CAS 1620445-17-1)
- Moxifloxacin Impurity 29 (CAS 1395056-41-3)
- Moxifloxacin Impurity 13 (CAS 1620445-13-7)
Recommended Standards
- tert-Butyl 3-cyano-2-(triphenylphosphoranylidene)propanoate (CAS 1998726-69-4)
- N-[2-(Aminosulfonyl)phenyl]-1-butyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamide (CAS 303776-59-2)
- N,N-Bis(1-methylethyl)dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (CAS 879083-07-5)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
- Ramelteon Impurity 23 (CAS 196597-30-5)
- Cefoperazone Impurity 39 (CAS CATO-C4X-114939)
- Ambroxol Impurity 41 (CAS CATO-C4X-108541)
- tert-Butyl 3-[(3-phenylpropyl)amino]propanoate (CAS 393154-28-4)
- N-(2,4-difluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide (CAS 946387-17-3)
- 4-Chloroisoquinolin-7-ol (CAS 1888902-20-2)
- N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)isonicotinamide (CAS 918493-44-4)
- 3-Chloro-1-isopropyl-7-methyl-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile (CAS 1774892-92-0)
- (2-cyclobutylethyl)(methyl)amine (CAS 1365939-73-6)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com