Moxifloxacin EP Impurity F CAS 721970-37-2
| CAS No. | 721970-37-2 |
| Molecular Formula | C22H26FN3O4 |
| Molecular Weight | 415.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Moxifloxacin EP Impurity F.
Moxifloxacin EP Impurity F (CAS 721970-37-2) is a certified pharmaceutical impurity reference standard with the molecular formula C22H26FN3O4 and a molecular weight of 415.46 g/mol.
Based on its molecular formula C22H26FN3O4, Moxifloxacin EP Impurity F contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O4 |
| Molecular Weight | 415.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Moxifloxacin Standards
- Moxifloxacin EP Impurity H (CAS 721970-35-0)
- Moxifloxacin Hydrochloride EP Impurity C (CAS 1029364-75-7)
- Moxifloxacin impurity 185 (CAS CATO-C4X-1074185)
- Moxifloxacin Impurity 192 (CAS CATO-C4X-1074192)
- Moxifloxacin Impurity 193 (CAS CATO-C4X-1074193)
- Moxifloxacin impurity 195 (CAS 1620445-17-1)
- Moxifloxacin Impurity 29 (CAS 1395056-41-3)
- Moxifloxacin Impurity 13 (CAS 1620445-13-7)
Recommended Standards
- tert-Butyl 3-cyano-2-(triphenylphosphoranylidene)propanoate (CAS 1998726-69-4)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
- N-[2-(Aminosulfonyl)phenyl]-1-butyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamide (CAS 303776-59-2)
- Tegoprazan Impurity 81 (CAS CATO-C4X-229781)
- Guanfacine Impurity 58 (CAS CATO-C4X-19758)
- Empagliflozin Impurity 21 (CAS CATO-C4X-106521)
- Metaraminol Impurity 27 (CAS 21480-43-3)
- Di-tert-butyl(((S)-6-((S)-2-amino-3-(naphthalen-2yl)propanamido)-1-(tert-butoxy)-1-oxohexan-2-yl)carbamoyl)-L-glutamate (CAS 2367588-01-8)
- 2-(6-Ethyl-4-oxoquinolin-1(4H)-yl)propanoic acid (CAS 1279201-34-1)
- 1-Bromo-2-methyl-4-vinylbenzene (CAS 90560-53-5)
- 1-(5-Methylfuran-2-yl)hexan-1-amine (CAS 1251074-96-0)
- Flupentixol Impurity 31 (CAS CATO-C4X-189531)
- (S)-2-Amino-2-cyclobutylethan-1-ol (CAS 1259702-72-1)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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