Esmolol Impurity 38 CAS 55226-78-3
| CAS No. | 55226-78-3 |
| Molecular Formula | C12H12O4 |
| Molecular Weight | 220.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Esmolol Impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Esmolol Impurity 38 (CAS 55226-78-3) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12O4 and a molecular weight of 220.22 g/mol.
The molecular framework of Esmolol Impurity 38 (C12H12O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H12O4 |
| Molecular Weight | 220.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Esmolol Standards
- Esmolol Impurity 20 (CAS 2167848-51-1)
- Esmolol Impurity 39 (CAS 54965-55-8)
- Esmolol Impurity 34 (CAS 7249-16-3)
- Esmolol Impurity 53 (CAS 5535-03-5)
- Esmolol Impurity 87 (CAS CATO-C4X-189187)
- Esmolol Impurity 60 (CAS CATO-C4X-189160)
- Esmolol Impurity 33 (CAS 27542-85-4)
- Esmolol Impurity 48 (CAS CATO-C4X-189148)
Recommended Standards
- Ubenimex Impurity 8 (CAS CATO-C4X-18528)
- Doxapram impurity 39 (CAS 2156014-06-9)
- Butylphthalide Impurity 39 (CAS 1485081-25-1)
- Fluralaner impurity 38 (CAS CATO-C4X-218038)
- Linagliptin Impurity 18 (CAS 668273-74-3)
- Mesalazine EP Impurity R (CAS 85-38-1)
- Baclofen impurity 11 (CAS CATO-C4X-101211)
- Methyl 3-amino-2,4-dimethylbenzoate (CAS 24812-89-3)
- 2-amino-3-(4-chloro-1H-pyrazol-1-yl)propanoic acid hydrochloride (CAS 1461705-98-5)
- n-(2-Chlorophenyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide (CAS 749215-81-4)
- 2-hydroxy-9,10-dihydroacridin-9-one (CAS 7466-73-1)
- 3-Amino-6-bromopyrazine-2-carboxamide (CAS 17890-77-6)
- Relebactam Impurity 116 (CAS 1978305-85-9)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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