(R)-2-(Fluoromethyl)piperazine CAS 725206-94-0

Purity 97%+In StockPharmaceutical Standards
CAS No.725206-94-0
Molecular FormulaC5H11FN2
Molecular Weight118.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-2-(Fluoromethyl)piperazine CAS 725206-94-0 chemical structure

Description

The occurrence of (R)-2-(Fluoromethyl)piperazine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(R)-2-(Fluoromethyl)piperazine (CAS 725206-94-0), molecular formula C5H11FN2 and molecular weight 118.15 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-2-(Fluoromethyl)piperazine (C5H11FN2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H11FN2
Molecular Weight118.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms2

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