(4S)-4-(fluoromethyl)tetrahydrofuran-2-one CAS 916069-80-2

Description

The occurrence of (4S)-4-(fluoromethyl)tetrahydrofuran-2-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(4S)-4-(fluoromethyl)tetrahydrofuran-2-one (CAS 916069-80-2), molecular formula C5H7FO2 and molecular weight 118.11 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (4S)-4-(fluoromethyl)tetrahydrofuran-2-one (C5H7FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (4S)-4-(fluoromethyl)tetrahydrofuran-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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