5-(Piperazin-1-ylmethyl)-6-(p-tolyl)imidazo[2,1-b]thiazole CAS 727975-67-9
| CAS No. | 727975-67-9 |
| Molecular Formula | C17H20N4S |
| Molecular Weight | 312.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(Piperazin-1-ylmethyl)-6-(p-tolyl)imidazo[2,1-b]thiazole (CAS 727975-67-9), molecular formula C17H20N4S and molecular weight 312.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(Piperazin-1-ylmethyl)-6-(p-tolyl)imidazo[2,1-b]thiazole (C17H20N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-(Piperazin-1-ylmethyl)-6-(p-tolyl)imidazo[2,1-b]thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20N4S |
| Molecular Weight | 312.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Piperazin Standards
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- 2-((2-(Piperazin-1-yl)ethyl)sulfonyl)benzo[d]thiazole (CAS 1707563-27-6)
- 4-[(4-Piperazin-1-ylphenyl)sulfonyl]morpholine (CAS 704873-20-1)
- 4-(2-(Piperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzonitrile (CAS 924229-14-1)
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Recommended Standards
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- N-(2-Cyano-3-methylbutan-2-yl)-2-(naphthalen-2-ylthio)acetamide (CAS 851472-52-1)
- 2-((3-Cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 445382-44-5)
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- 2-(2-methylpropyl)pyridine (CAS 6304-24-1)
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- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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