4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate CAS 72860-48-1

Purity 97%+In StockPharmaceutical Standards
CAS No.72860-48-1
Molecular FormulaC11H4Cl2F3NO2S
Molecular Weight342.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate CAS 72860-48-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate.

CATO supplies 4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 72860-48-1), a certified reference material (molecular formula C11H4Cl2F3NO2S, MW 342.12 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 342.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chlorophenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H4Cl2F3NO2S
Molecular Weight342.12 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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