Bortezomib Impurity 40 CAS 87304-47-0
| CAS No. | 87304-47-0 |
| Molecular Formula | C15H26BClO2 |
| Molecular Weight | 284.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bortezomib Impurity 40.
CATO supplies Bortezomib Impurity 40 (CAS 87304-47-0), a pharmacopoeial impurity reference standard (molecular formula C15H26BClO2, MW 284.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Bortezomib Impurity 40 (C15H26BClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bortezomib Impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H26BClO2 |
| Molecular Weight | 284.63 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
Related Bortezomib Standards
- Bortezomib Impurity N46 (CAS 85167-14-2)
- Bortezomib Impurity 33 (CAS 73058-37-4)
- Bortezomib Impurity 49 (CAS 948294-96-0)
- Bortezomib Impurity 67 (CAS 2308-61-4)
- Bortezomib Impurity 2 (CAS 114457-94-2)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- Bortezomib Impurity 16 (CAS CATO-C4X-107216)
- Bortezomib Impurity 29 (CAS CATO-C4X-107229)
Recommended Standards
- Isopropyl 2-chloro-5-fluoro-3-(trifluoromethyl)benzoate (CAS 2364585-36-2)
- 3-(3-Chloro-4-fluorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (CAS 1283108-59-7)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)acetonitrile (CAS 1823182-69-9)
- 2-Chloro-1,1,1-Trifluoro-6-Methyl-2-(Trifluoromethyl)Heptan-4-One (CAS 101913-92-2)
- Nintedanib Impurity 129 (CAS CATO-C4X-1814129)
- Vonoprazan Impurity 115 (CAS CATO-C4X-1020115)
- Trimebutine Impurity 17 (CAS CATO-C4X-185817)
- N-Nitroso-N,N-di(3,5,5-trimethylhexyl)amine-d (CAS 1346603-10-8)
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- 4-Methoxy-3-(1-methyl-1H-pyrazol-4-yl)aniline (CAS 1351382-51-8)
- Cinmethylin (CAS 87818-31-3)
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol (CAS 1583260-13-2)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-3-cyanopropan-2-yl furan-2-carboxylate (CAS 339016-45-4)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com