2,3:5,6-Di-O-isopropylidene-L-gulonolactone CAS 7306-64-1
| CAS No. | 7306-64-1 |
| Molecular Formula | C12H18O6 |
| Molecular Weight | 258.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3:5,6-Di-O-isopropylidene-L-gulonolactone.
2,3:5,6-Di-O-isopropylidene-L-gulonolactone (CAS 7306-64-1), molecular formula C12H18O6 and molecular weight 258.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3:5,6-Di-O-isopropylidene-L-gulonolactone (C12H18O6) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18O6 |
| Molecular Weight | 258.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Recommended Standards
- 2,3:5,6-DI-o-isopropylidene-d-talonoic acid-1,4-lactone (CAS 23262-80-8)
- 2',4'-Dimethoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 728919-16-2)
- 2,2-Bis(4-hydroxyphenyl)propanoic acid (CAS 92549-67-2)
- 2,5-Dihydro-2-oxo-5-phenyl-5-(2-propenyl)-3-furancarboxylicacid,methylester (CAS 844437-52-1)
- tert-Butyl 4-[6-(4-chlorophenyl)-5-cyano-2-(pyridin-4-yl)pyrimidin-4-yl]piperazine-1-carboxylate (CAS 383148-76-3)
- 5-[3-(Isopropylsulfonyl)phenyl]-1,3,4-oxadiazol-2-amine (CAS 1105194-09-9)
- 6,7,8,9-Tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepine-3-carboxylic acid (CAS 1177311-87-3)
- tert-Butyl 6-benzyl-2,3,4,5,6,6a-hexahydroindeno[1,2-b:3,2-b']dipyrrole-1(10bH)-carboxylate (CAS 2621395-77-3)
- Persicoside (CAS 28978-03-2)
- 2-Bromo-4-(pyridin-4-yl)thiazole (CAS 886371-01-3)
- [(2-Bromo-3-methoxyphenyl)methyl](methyl)amine (CAS 1509239-12-6)
- 2-((2-((4-Fluorobenzyl)amino)-2-oxoethyl)thio)acetic acid (CAS 338794-24-4)
- Ixazomib Impurity 29 (CAS 1201903-03-8)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
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