Fluticasone Propionate EP Impurity D CAS 73205-13-7
| CAS No. | 73205-13-7 |
| Molecular Formula | C25H32F2O5S |
| Molecular Weight | 482.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Fluticasone Propionate EP Impurity D (CAS 73205-13-7) is a certified pharmaceutical impurity reference standard with the molecular formula C25H32F2O5S and a molecular weight of 482.58 g/mol.
Fluticasone Propionate EP Impurity D (C25H32F2O5S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Fluticasone Propionate EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H32F2O5S |
| Molecular Weight | 482.58 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity 98 (CAS 709002-84-6)
- Fluticasone Propionate Fluoromethyl Ester Analog (CAS 1174034-79-7)
- Fluticasone Propionate EP Impurity B (CAS 948566-12-9)
- Fluticasone Impurity 41 (CAS 192191-49-4)
- Fluticasone Propionate Dithioacid (CAS CATO-C4X-165047)
- Fluticasone Impurity 39 (CAS CATO-C4X-165039)
- Fluticasone Impurity 50 (CAS CATO-C4X-165050)
- Fluticasone Furoate EP Impurity B (CAS 80474-24-4)
Recommended Standards
- Fasudil Dimer Impurity (CAS 1337967-93-7)
- Atrasentan Impurity 23 (CAS 1058393-35-3)
- Phosphine, 1,2-ethanediylbis[[2-(1-methylethyl)phenyl]phenyl-, (1S,1′S)- (CAS 794526-19-5)
- Atrasentan Impurity 28 (CAS 1073590-44-9)
- Fasudil Impurity 69 (CAS CATO-C4X-136569)
- Medroxyprogesterone Impurity 15 (CAS CATO-C4X-145715)
- Thiotepa Impurity 6 (CAS CATO-C4X-21566)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com