Fluticasone Furoate EP Impurity B CAS 80474-24-4
| CAS No. | 80474-24-4 |
| Molecular Formula | C24H29F3O5S |
| Molecular Weight | 486.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 486.54 g/mol gives Fluticasone Furoate EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Fluticasone Furoate EP Impurity B (CAS 80474-24-4), a pharmacopoeial impurity reference standard (molecular formula C24H29F3O5S, MW 486.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Fluticasone Furoate EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 486.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fluticasone Furoate EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H29F3O5S |
| Molecular Weight | 486.54 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity 50 (CAS CATO-C4X-165050)
- Fluticasone Impurity 39 (CAS CATO-C4X-165039)
- Fluticasone Propionate Dithioacid (CAS CATO-C4X-165047)
- Fluticasone Propionate EP Impurity B (CAS 948566-12-9)
- Fluticasone Propionate Fluoromethyl Ester Analog (CAS 1174034-79-7)
- Fluticasone Impurity 98 (CAS 709002-84-6)
- Fluticasone Furoate EP Impurity A (CAS 397864-63-0)
- Fluticasone Propionate EP Impurity D (CAS 73205-13-7)
Recommended Standards
- Raltitrexed Impurity 35 (CAS CATO-C4X-138635)
- ACTH (1-4) (CAS 19405-50-6)
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- (((16,16,17,17,18,18,18-Heptafluorooctadecyl)oxy)methyl)benzene (CAS 102197-77-3)
- Mianserin impurity 22 (CAS CATO-C4X-136922)
- Spironolactone EP Impurity C (CAS 976-70-5)
- Tocopherol Impurity 14 (CAS CATO-C4X-119514)
- piperidin-2-ylmethyl N-propylcarbamate hydrochloride (CAS 1803562-46-0)
- 1,3-Dioxooctahydroisobenzofuran-5,6-dicarboxylic acid (CAS 676642-36-7)
- 2-Amino-4-(4-methylpiperidin-1-yl)butanamide (CAS 1310082-93-9)
- 1-(5-Hydroxy-4-methyltetrahydrofuran-3-yl)ethanone (CAS 113531-94-5)
- (R)-2-(benzyl((4-bromo-1H-pyrazol-5-yl)methyl)amino)propan-1-ol (CAS 1639881-03-0)
- N-Acetyl-3-acetoxyindole (CAS 16800-67-2)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com