Tazarotene impurity 2 CAS 7335-27-5
| CAS No. | 7335-27-5 |
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tazarotene impurity 2.
CATO supplies Tazarotene impurity 2 (CAS 7335-27-5), a pharmacopoeial impurity reference standard (molecular formula C9H9ClO2, MW 184.62 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tazarotene impurity 2 (C9H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tazarotene impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Tazarotene Standards
Recommended Standards
- Dyclonine Impurity 21 (CAS 7182-38-9)
- Zopiclone Impurity 2 (CAS 13606-92-3)
- Dyclonine Impurity 20 (CAS 35999-21-4)
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- Imatinib Impurity 95 (CAS 1642630-12-3)
- Enzalutamide Impurity 43 (CAS CATO-C4X-101643)
- Tizanidine impurity 19 (CAS 65959-12-8)
- Paliperidone Impurity 107 HCl (CAS CATO-C4X-1724107)
- 1-(4-Ethylphenyl)-6-methoxy-4-methyl-1H,2H,3H-pyrrolo[3,2-c]quinoline (CAS 860789-56-6)
- tert-butyl N-(4-aminobutyl)-N-(benzyloxy)carbamate (CAS 1027408-37-2)
- (R)-3-azaspiro[5.5]Undecan-7-amine dihydrochloride (CAS 2306254-00-0)
- Venlafaxine Impurity 58 (CAS 1000377-27-4)
- 2-Methoxy-4-phenylphenol (CAS 37055-79-1)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com