Zopiclone Impurity 2 CAS 13606-92-3
| CAS No. | 13606-92-3 |
| Molecular Formula | C8H9ClN2O |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Zopiclone Impurity 2 (CAS 13606-92-3, C8H9ClN2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Zopiclone Impurity 2 (C8H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Zopiclone Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2O |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Zopiclone Standards
- Zopiclone Impurity 16 (CAS 59325-11-0)
- Zopiclone Impurity 12 (CAS 45965-30-8)
- Zopiclone Impurity 9 (CAS 39539-66-7)
- Zopiclone impurity 28 (CAS 69433-07-4)
- Zopiclone Impurity 15 (CAS 4180-30-7)
- Zopiclone Impurity 18 (CAS 349125-10-6)
- Zopiclone EP Impurity C (CAS 148891-53-6)
- Zopiclone EP Impurity B (CAS 43200-81-3)
Recommended Standards
- Tazarotene impurity 2 (CAS 7335-27-5)
- 3-(3-Chloro-2-hydroxypropoxy)propane-1,2-diol (CAS 52550-57-9)
- Dyclonine Impurity 21 (CAS 7182-38-9)
- 1-(3-Chloro-4-methylphenyl)urea (CAS 13142-64-8)
- Avibactam Impurity 138 Acetate (CAS 2306254-34-0（free base）)
- Blonanserin Impurity 19 (CAS CATO-C4X-111019)
- Lanreotide Impurity 12 (CAS CATO-C4X-237012)
- tert-Butyl azepane-1-carboxylate (CAS 123387-52-0)
- Fenazaquin Impurity 3 (CAS 124428-11-1)
- 2,3-Difluoro-5-methylbenzonitrile (CAS 1003712-18-2)
- Thiamine /Vitamin B1 Impurity 54 Ammonium Salt (CAS 10553-88-5 (free form))
- 4-[2-(4-Piperidinylmethoxy)ethyl]morpholine (CAS 946680-57-5)
- Tenofovir alafenamide Impurity 97 (CAS CATO-C4X-179797)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com