Niclosamide Monohydrate CAS 73360-56-2
| CAS No. | 73360-56-2 |
| Molecular Formula | C13H8Cl2N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H8Cl2N2O4H2O, Niclosamide Monohydrate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 345.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Niclosamide Monohydrate (CAS 73360-56-2), molecular formula C13H8Cl2N2O4H2O and molecular weight 345.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Niclosamide Monohydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2N2O4 H2O |
| Molecular Weight | 345.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Niclosamide Standards
- 13C6-Niclosamide hydrate (CAS 1325559-12-3)
- Niclosamide-13C6 (CAS 1325808-64-7)
- Niclosamide ethanolamine salt (CAS 1420-04-8)
- Niclosamide Impurity 2 (CAS 16739-20-1)
- Niclosamide Impurity 4 (CAS 16739-21-2)
- Niclosamide Impurity 5 (CAS 32853-24-0)
- Niclosamide Piperazine Salt (CAS 34892-17-6)
- Niclosamide Impurity 3 (CAS 4638-49-7)
Recommended Standards
- (3S,3AS,6S)-3-((tert-Butyldimethylsilyl)oxy)-6-(hydroxymethyl)-3a,6-dimethyldecahydro-1H-cyclopenta[a]naphthalen-7(2H)-one (CAS 327048-93-1)
- 4-chloro-3-methyl-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid (CAS 1779968-91-0)
- 2-(5,6,7,8-tetrahydro-2-naphthalenyloxy)butanoic acid (CAS 869947-98-8)
- 2-(((1-Methoxypropan-2-yl)amino)methyl)-4-methylphenol (CAS 1342881-88-2)
- 1,3 Di-n-octyloxy Calix(4)arene crown-6 stereoisomer (CAS 161282-97-9)
- (2S)-2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid hydrochloride (CAS 63302-24-9)
- Dendrobine (CAS 2115-91-5)
- 1-[(3-Methoxyphenyl)methyl]-1,4-diazepane (CAS 502142-36-1)
- (R)-Ethyl 2-acetamido-3-mercaptopropanoate (CAS 59587-09-6)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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