Esomeprazole EP Impurity C CAS 73590-85-9
| CAS No. | 73590-85-9 |
| Molecular Formula | C17H19N3O2S |
| Molecular Weight | 329.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Esomeprazole EP Impurity C.
As a process- or degradation-related impurity, Esomeprazole EP Impurity C (CAS 73590-85-9, C17H19N3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Esomeprazole EP Impurity C (C17H19N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Esomeprazole EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O2S |
| Molecular Weight | 329.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole impurity 126 (CAS CATO-C4X-1112126)
- Esomeprazole Impurity 119 (CAS CATO-C4X-1112119)
- Esomeprazole Impurity 120 (CAS 358675-51-1)
- Esomeprazole Impurity 17 (CAS 151602-49-2)
- Esomeprazole Impurity 136 (CAS 2561418-28-6)
- Esomeprazole impurity 138 (CAS CATO-C4X-1112138)
- Esomeprazole impurity 133 (CAS CATO-C4X-1112133)
- Esomeprazole Impurity 121 (CAS CATO-C4X-1112121)
Recommended Standards
- N-Phenyl-2-(5-phenyl-1,3,4-thiadiazol-2-yl)aniline (CAS 88518-09-6)
- Rabeprazole Impurity 7 (CAS 117976-91-7)
- N-Cyclohexyl-N-ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide (CAS 874806-83-4)
- Peficitinib-d3 (CAS CATO-C4X-280717)
- Trazodone Impurity 7 (CAS 53818-10-3)
- Sulbenicillin Impurity 2 (CAS CATO-C4X-23242)
- Rosuvastatin EP Impurity M(Sodium Salt) (CAS 847849-66-5(free base))
- Tert-butyl N-[3-(chloromethyl)phenyl]carbamate (CAS 219706-58-8)
- N-[4-(isothiocyanatomethyl)-1,3-thiazol-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 790681-65-1)
- 1-[2-(4-Piperidinyl)ethyl]azepane dihydrochloride (CAS 1220035-80-2)
- 4-Amino-2'-methoxy[1,1'-biphenyl]-3-carboxylic acid (CAS 893735-62-1)
- Cyclobutyl(3-(trifluoromethyl)phenyl)methanamine hydrochloride (CAS 1803598-33-5)
- [1,3'-biazetidin]-3-oloxalate (CAS 1523606-25-8)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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