Trazodone Impurity 7 CAS 53818-10-3
| CAS No. | 53818-10-3 |
| Molecular Formula | C19H22ClN5O2 |
| Molecular Weight | 387.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C19H22ClN5O2, Trazodone Impurity 7 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 387.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Trazodone Impurity 7 (CAS 53818-10-3) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22ClN5O2 and a molecular weight of 387.86 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22ClN5O2 |
| Molecular Weight | 387.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone Impurity 110 (CAS CATO-C4X-1772110)
- Trazodone EP Impurity A (CAS 55290-68-1)
- Trazodone impurity 62 (CAS CATO-C4X-177262)
- Trazodone Impurity 85 (CAS CATO-C4X-177285)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- Trazodone EP Impurity C (CAS 157072-19-0)
- Trazodone Hydrochloride EP Impurity M (CAS 157072-18-9 (cation form))
Recommended Standards
- Z-Dimethomorph (CAS 113210-98-3)
- Dimethomorph (CAS 110488-70-5)
- N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)acetamide (CAS 499197-54-5)
- 7-Chloro-4-((3-(trifluoromethyl)benzyl)thio)-2,3-dihydrobenzo[b][1,4]thiazepine (CAS 477855-80-4)
- Indobufen Impurity N5 (CAS 15494-55-0)
- (Z)-Ceftizoxime Impurity 18 (CAS CATO-C4X-179318)
- Dienogest EP Impurity E (CAS 102193-41-9)
- 2-(Quinazolin-4-yloxy)acetic acid (CAS 842959-64-2)
- 2-{3-azabicyclo[3.3.1]nonan-9-yl}acetic acid hydrochloride (CAS 2060009-09-6)
- 1-(4-Fluorophenyl)-N-(1-((4-methoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide (CAS 946346-88-9)
- 2,5-Dibenzylidenecyclopentanone (CAS 34611-43-3)
- 4-(2-(5-(4-Methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetamido)benzoic acid (CAS 303026-03-1)
- 3-Fluoro-4-(2-hydroxyethoxy)benzonitrile (CAS 917226-74-5)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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