2-Chloro-N-methyl-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide CAS 7365-23-3
| CAS No. | 7365-23-3 |
| Molecular Formula | C7H12ClNO3S |
| Molecular Weight | 225.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-N-methyl-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide (CAS 7365-23-3), a certified reference material (molecular formula C7H12ClNO3S, MW 225.69 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-N-methyl-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide (C7H12ClNO3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H12ClNO3S |
| Molecular Weight | 225.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-n-(1,1-dioxo-1λ6-thian-4-yl)acetamide (CAS 1107645-27-1)
- 4-Chloro-6-(methylsulfinyl)quinoline (CAS 1161837-88-2)
- 2-Chloro-n-[(1,1-dioxo-1lambda6-thiolan-3-yl)methyl]acetamide (CAS 1179593-48-6)
- 2-(5-Chloro-2-thienyl)-6-methoxypyridine (CAS 1187168-49-5)
- 5-Chloro-8-methoxyquinoline-4(1H)-thione (CAS 1315345-11-9)
- 4-Chloro-2-(2-methylthiazol-4-yl)phenol (CAS 1387575-84-9)
- 2-Chloro-4-(4-methoxyphenyl)thiazole (CAS 2104-01-0)
- 2-Chloro-5-(phenoxymethyl)thiazole (CAS 339018-23-4)
Recommended Standards
- 2-Chloro-n-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)acetamide (CAS 790272-36-5)
- 3-chloro-1-(1,1-dioxidothiomorpholino)propan-1-one (CAS 883797-57-7)
- 2-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)propanamide (CAS 879361-50-9)
- 3-Chloro-6-methylbenzo[b]thiophene-2-carboxamide (CAS 34586-87-3)
- (R)-3-N-Butylphthalide (CAS 125412-70-6)
- (3-(Aminomethyl)piperidin-1-yl)(3-fluorophenyl)methanone (CAS 1018554-52-3)
- 2,2'-(2,5-Bis((2-ethylhexyl)oxy)-1,4-phenylene)dithiophene (CAS 928853-15-0)
- 7-(But-2-en-1-yl)-3-methyl-8-(2-(1-phenylethylidene)hydrazinyl)-3,7-dihydro-1H-purine-2,6-dione (CAS 303973-97-9)
- 4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid (CAS 2387601-71-8)
- 7-Iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-8-ol (CAS 1246088-40-3)
- Furosemide Impurity 8 (CAS 41332-59-6)
- 2-(methylsulfanyl)-3h,4h-pyrrolo[2,1-f][1,2,4]triazin-4-one (CAS 1232815-50-7)
- N-Methoxy-N,4-dimethyl-1-naphthamide (CAS 1807542-90-0)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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