Avanafil Impurity 102 DiHCl CAS 73706-74-8
| CAS No. | 73706-74-8 |
| Molecular Formula | C5H11N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avanafil Impurity 102 DiHCl.
As a process- or degradation-related impurity, Avanafil Impurity 102 DiHCl (CAS 73706-74-8, C5H11N3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to chlorine substitution, Avanafil Impurity 102 DiHCl is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11N3 2*HCl |
| Molecular Weight | 149.62 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Avanafil Standards
- Avanafil Impurity 77 (CAS 1201936-61-9)
- Avanafil Impurity 160 (CAS 1202002-16-1)
- Avanafil Impurity 3 (CAS 1364671-52-2)
- Avanafil Impurity 2 (CAS 1364671-62-4)
- Avanafil Impurity 110 (CAS 1368440-33-8)
- Avanafil Impurity 4 (CAS 1452128-53-8)
- Avanafil Impurity 133 (CAS 1508194-63-5)
- Avanafil Impurity 46 (CAS 1624833-89-1)
Recommended Standards
- Argatroban Impurity N2 (CAS 79672-38-1)
- Tadalafil Impurity 11 HCl (CAS 1190238-20-0)
- Dienogest EP Impurity K (CAS 106111-43-7)
- 2,2,2-Trifluoroacetic acid compound with 2-(azetidin-3-yl)acetic acid (1:1) (CAS 1202076-02-5)
- N-(4-Isopropyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)thiophene-2-carboxamide (CAS 1404437-62-2)
- Ethyl 4-(4-bromophenyl)-1-piperazinecarboxylate (CAS 1226808-66-7)
- (3R,4S)-4-fluoro-1-methyl-piperidin-3-amine;dihydrochloride (CAS 2306248-19-9)
- 4-Bromo-1-(2-fluoroethyl)-1h-pyrazole (CAS 1049730-35-9)
- Ethyl 2-(3-(trifluoromethyl)phenyl)acetate (CAS 331-33-9)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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