Avanafil Impurity 110 CAS 1368440-33-8
| CAS No. | 1368440-33-8 |
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Avanafil Impurity 110 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Avanafil Impurity 110 (CAS 1368440-33-8), a pharmacopoeial impurity reference standard (molecular formula C8H9Cl2NO, MW 206.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Avanafil Impurity 110 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2NO |
| Molecular Weight | 206.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Avanafil Standards
- Avanafil Impurity 133 (CAS 1508194-63-5)
- Avanafil Impurity 25 (CAS 36167-94-9)
- Avanafil Impurity 160 (CAS 1202002-16-1)
- Avanafil Impurity 55 (CAS 5909-24-0)
- Avanafil Impurity 70 (CAS 32897-26-0)
- Avanafil Impurity 108 (CAS CATO-C4X-1118108)
- Avanafil Impurity 111 (CAS CATO-C4X-1118111)
- Avanafil Impurity 33 (CAS 247569-72-8)
Recommended Standards
- rel-(3aR,6aS)-2-Phenyltetrahydrothieno[3,4-d][1,3,2]dioxaborole (CAS 62729-30-0)
- Pyridine, 2,6-dichloro-4-(1-methoxyethyl)- (CAS 2757008-61-8)
- N1-(3,5-Dichloropyridin-2-yl)ethane-1,2-diamine (CAS 253309-39-6)
- Ilaprazole impurity 198 (CAS CATO-C4X-1130198)
- Quinapril Hydrochloride EP Impurity H (CAS CATO-C4X-17415)
- Levetiracetam EP Impurity A (CAS 103833-72-3)
- Azathioprine EP Impurity G (Thiamiprine) (CAS 5581-52-2)
- Na in water quality (CAS CATO-CQCM102194)
- 4-Hydroxy-3-((E)-(4-((E)-(2-methoxy-5-((2-(sulfooxy)ethyl)sulfonyl)phenyl)diazenyl)-7-sulfonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonic acid (CAS 37395-77-0)
- Crocetin dimethyl ester (CAS 5892-54-6)
- 2-(2-Oxopropyl)phenoxyacetic acid (CAS 412962-61-9)
- 6-Methyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine (CAS 489425-91-4)
- n-Allyl-1-(4-bromophenyl)cyclopropane-1-carboxamide (CAS 1456018-94-2)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com