Tacrolimus EP Impurity G CAS 144490-63-1
| CAS No. | 144490-63-1 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tacrolimus EP Impurity G is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Tacrolimus EP Impurity G (CAS 144490-63-1, C44H69NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C44H69NO12, Tacrolimus EP Impurity G contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 804.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tacrolimus EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Purity | >80% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus (CAS 104987-11-3)
- Tacrolimus Impurity 15 (CAS CATO-C4X-130015)
- Tacrolimus Impurity 17 (CAS CATO-C4X-130017)
- Tacrolimus EP Impurity F (CAS 1393890-33-9)
- Tacrolimus Impurity 36 (CAS 131944-48-4)
- Tacrolimus Impurity 37 (CAS CATO-C4X-130037)
- Tacrolimus Impurity 38 (CAS CATO-C4X-130038)
- Tacrolimus Impurity 43 (CAS CATO-C4X-130043)
Recommended Standards
- (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity (CAS CATO-C4X-130012)
- Tacrolimus Impurity 47 (CAS CATO-C4X-130047)
- [Lys5,MeLeu9,Nle10]-Neurokinin A (4-10) Fragment (CAS 137565-28-7)
- Tacrolimus Impurity 55 (CAS CATO-C4X-130055)
- Voglibose Impurity 3 (CAS 83465-22-9)
- Picosulfate impurity 27 (CAS CATO-C4X-123727)
- Benzylpenicillin EP Impurity F (2R,4S-Isomer) (CAS 73184-06-2)
- 4-[2-(1-Morpholinyl)ethoxy]benzophenone (CAS 102178-03-0)
- (4-(5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)phenyl)methanamine (CAS 1489490-62-1)
- 1-(3-Methyl-5-thioxo-4,5-dihydro-1H-pyrazol-4-yl)ethanone (CAS 211988-12-4)
- 7-Methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carbaldehyde (CAS 1710345-17-7)
- tert-Butyl 3-(hydroxymethyl)-2-oxa-7-azaspiro[4.5]decane-7-carboxylate (CAS 1251002-30-8)
- Isopropyl 3-[(chloroacetyl)amino]benzoate (CAS 6307-69-3)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com