Dexamethasone impurity 78 CAS 1879-72-7
| CAS No. | 1879-72-7 |
| Molecular Formula | C31H37FO6 |
| Molecular Weight | 524.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone impurity 78 (CAS 1879-72-7) is a certified pharmaceutical impurity reference standard with the molecular formula C31H37FO6 and a molecular weight of 524.62 g/mol.
Dexamethasone impurity 78 (C31H37FO6) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone impurity 78 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H37FO6 |
| Molecular Weight | 524.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 01 (CAS 83880-70-0)
- Dexamethasone Impurity 118 (CAS CATO-C4X-1165118)
- Dexamethasone Impurity 119 (CAS CATO-C4X-1165119)
- Dexamethasone Impurity 113 (CAS CATO-C4X-1165113)
- Dexamethasone impurity 80 (CAS CATO-C4X-116580)
- Dexamethasone impurity 81 (CAS CATO-C4X-116581)
- Dexamethasone Impurity 84 (CAS CATO-C4X-116584)
- Dexamethasone Impurity 87 (CAS CATO-C4X-116587)
Recommended Standards
- PEG8-Tos (CAS 886469-23-4)
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- Fmoc-Ser(tBu)-Thr(Psi(Me,Me)pro)-OH (CAS 1266350-99-5)
- Cefminox Impurity 26 (CAS CATO-C4X-192626)
- Atogepant Impurity 63 (CAS CATO-C4X-328563)
- Aztreonam Impurity 115 (CAS CATO-C4X-1522115)
- Epinephrine /Adrenaline Impurity 130 (CAS CATO-C4X-1849130)
- Methyl 5-bromo-2-chloro-3-methylbenzoate (CAS 1263377-05-4)
- [1,2,4]Triazolo[4,3-a]quinoxaline (CAS 235-08-5)
- 4-ethoxy-1,1-difluorobut-3-en-2-one (CAS 375856-23-8)
- 2-Methoxy-5-(5-methylthiophen-3-yl)aniline (CAS 1496124-39-0)
- 3-[5-(5-Ethyl-1-methyl-1H-pyrazol-3-yl)-1,3,4-oxadiazol-2-yl]propanoic acid (CAS 1365962-65-7)
- 2-O-(tert-Butyldimethylsilyl)paclitaxel 7-O-triflate (CAS 165065-01-0)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com