Captopril impurity 41 CAS 74190-08-2
| CAS No. | 74190-08-2 |
| Molecular Formula | C9H13NO2S |
| Molecular Weight | 199.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Captopril impurity 41.
As a process- or degradation-related impurity, Captopril impurity 41 (CAS 74190-08-2, C9H13NO2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Captopril impurity 41 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 199.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Captopril impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13NO2S |
| Molecular Weight | 199.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Captopril Standards
- Captopril Impurity 35 (CAS 613256-52-3)
- Captopril EP Impurity E (CAS 23500-15-4)
- Captopril Impurity 37(Piracetam Impurity E) (CAS 1249080-59-8)
- Captopril Impurity 26 (CAS 51161-88-7)
- Captopril EP Impurity F (CAS 63250-36-2)
- D-Captopril (CAS 119238-52-7)
- Captopril Related Compound 8 (CAS 112243-88-6)
- Captopril (CAS 62571-86-2)
Recommended Standards
- 93447-77-9 ethyl 3-amino-3-(2-thienyl)propanoate hydrochloride (CAS 93447-77-9)
- Promethazine EP Impurity A (CAS 92-84-2)
- 66893-81-0 B1735 N-(4-Pyridylmethylene)-tert-butylamine N,N'-Dioxide N-tert-Butyl-alpha-(4-pyridyl)nitrone N'-Oxide N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone POBN alpha-(4-Pyridyl N-Oxide)-N-tert-butylnitrone (CAS 66893-81-0)
- Promethazine Impurity 74 (CAS CATO-C4X-141874)
- Lacidipine Impurity 26 (CAS CATO-C4X-167126)
- Mianserin Impurity 53 (CAS CATO-C4X-136953)
- Salbutamol EP Impurity N(Trifluoroacetic Acid) (CAS CATO-C4X-117641)
- 9-Bromo-3,4-dihydro-2h-1,5-benzodioxepine-7-carbaldehyde (CAS 1094419-43-8)
- (R)-Ethyl 4-benzylmorpholine-3-carboxylate (CAS 106910-85-4)
- 3-(Benzofuran-2-yl)-1H-pyrazole (CAS 666728-39-8)
- Cefixime Impurity 13 (CAS CATO-C4X-113913)
- Ramosetron Impurity 20 (CAS 32387-21-6)
- 5-Amino-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1190322-68-9)
- Semaglutide impurity 29 (CAS 110990-08-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com