Promethazine EP Impurity A CAS 92-84-2
| CAS No. | 92-84-2 |
| Molecular Formula | C12H9NS |
| Molecular Weight | 199.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Promethazine EP Impurity A is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Promethazine EP Impurity A (CAS 92-84-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H9NS and a molecular weight of 199.27 g/mol.
Structurally, Promethazine EP Impurity A (C12H9NS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 199.27 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Promethazine EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9NS |
| Molecular Weight | 199.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Promethazine Standards
- Promethazine Impurity 74 (CAS CATO-C4X-141874)
- Promethazine Impurity 28 (CAS 36144-72-6)
- Promethazine Impurity 30 (CAS 3568-81-8)
- Promethazine Impurity 16 (CAS CATO-C4X-141816)
- Promethazine Impurity 27 (CAS 1209-66-1)
- Promethazine Impurity 29 (CAS 20962-92-9)
- Promethazine Impurity 7 (CAS 15375-48-1)
- Promethazine impurity 58 (CAS CATO-C4X-141858)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com