Dopamine Impurity 86 CAS 74321-37-2
| CAS No. | 74321-37-2 |
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Dopamine Impurity 86 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Dopamine Impurity 86 (CAS 74321-37-2) is a certified pharmaceutical impurity reference standard with the molecular formula C10H15NO2 and a molecular weight of 181.23 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
Related Dopamine Standards
- Dopamine Impurity 14 (CAS 21581-37-3)
- Dopamine Impurity 29 (CAS 15806-29-8)
- Dopamine Impurity 31 (CAS 3213-28-3)
- Dopamine Impurity 75 (CAS 32602-66-7)
- Dopamine EP Impurity C (CAS 120-20-7)
- Dopamine Impurity 85 (CAS 763024-20-0)
- Dopamine Impurity 94 (CAS CATO-C4X-190894)
- Dopamine Impurity 3 (CAS 108074-44-8)
Recommended Standards
- Metaraminol Impurity 78 (CAS 65133-68-8)
- Metaraminol Impurity 87 (CAS CATO-C4X-225287)
- 2-Diethylamino-6-Methyl-4-Pyrimidinol (CAS 42487-72-9)
- 2-Aminofluorene (CAS 153-78-6)
- Roxatidine Impurity 51 (CAS CATO-C4X-121351)
- Thymalfasin Impurity 8 (CAS CATO-C4X-18988)
- Azathioprine EP Impurity C (CAS 4897-25-0)
- 3-Bromo-5-(piperidin-1-yl)phenol (CAS 1820640-16-1)
- 5-Amino-1H-pyrrole-3-carbonitrile (CAS 1211524-41-2)
- 3-Methyl-4-nonanone (CAS 35778-39-3)
- 1-(tert-Butyl)-3-(2-(furan-2-yl)-2-(indolin-1-yl)ethyl)urea (CAS 898458-06-5)
- 4-Methylene-5-hexen-1-ol (CAS 17844-23-4)
- 2-((3-((3-Chlorophenyl)carbamoyl)phenyl)carbamoyl)benzoic acid (CAS 307338-57-4)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
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