3-(2,2-dimethyltetrahydropyran-4-yl)prop-2-ynoic acid CAS 74376-72-0

Purity 97%+In StockPharmaceutical Standards
CAS No.74376-72-0
Molecular FormulaC10H14O3
Molecular Weight182.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,2-dimethyltetrahydropyran-4-yl)prop-2-ynoic acid CAS 74376-72-0 chemical structure

Description

3-(2,2-dimethyltetrahydropyran-4-yl)prop-2-ynoic acid (CAS 74376-72-0), molecular formula C10H14O3 and molecular weight 182.22 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(2,2-dimethyltetrahydropyran-4-yl)prop-2-ynoic acid (C10H14O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(2,2-dimethyltetrahydropyran-4-yl)prop-2-ynoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H14O3
Molecular Weight182.22 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978

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