2-Chloro-1-methyl-4-(trifluoromethyl)benzene CAS 74483-47-9
| CAS No. | 74483-47-9 |
| Molecular Formula | C8H6ClF3 |
| Molecular Weight | 194.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-1-methyl-4-(trifluoromethyl)benzene (CAS 74483-47-9) is a high-purity analytical reference standard with the molecular formula C8H6ClF3 and a molecular weight of 194.58 g/mol.
Structurally, 2-Chloro-1-methyl-4-(trifluoromethyl)benzene (C8H6ClF3) contains fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 194.58 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3 |
| Molecular Weight | 194.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-6-methylbenzotrifluoride 1-Chloro-3-methyl-2-(trifluoromethyl)benzene 112641-25-5 (CAS 112641-25-5)
- 2-Chloro-4-(1,1-difluoroethyl)-1-fluorobenzene (CAS 1138444-93-5)
- 1-Chloro-3-methyl-5-(trifluoromethyl)benzene (CAS 1214384-22-1)
- 1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene (CAS 1221272-76-9)
- 4-Chloro-2-methylbenzotrifluoride (CAS 13630-22-3)
- 1-Chloro-2-(2,2,2-trifluoroethyl)benzene (CAS 145914-05-2)
- 4-Chloro-1-methyl-2-(trifluoromethyl)benzene (CAS 1839-92-5)
- (1-Chloro-2,2,2-trifluoroethyl)benzene (CAS 384-65-6)
Recommended Standards
- 2-(Trifluoromethyl)benzyl Chloride (CAS 21742-00-7)
- 2-Chloro-3-methylbenzotrifluoride (CAS 74483-48-0)
- 1-Chloro-4-(2,2,2-trifluoroethyl)benzene (CAS 81577-07-3)
- 2-Chloro-4-methyl-1-(trifluoromethyl)benzene (CAS 74483-46-8)
- 1-(4-((4-Fluorobenzyl)oxy)-3-methoxyphenyl)ethan-1-one (CAS 890092-12-3)
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