Atorvastatin Calcium EP Impurity F CAS 887196-24-9
| CAS No. | 887196-24-9 |
| Molecular Formula | C40H48FN3O8 |
| Molecular Weight | 717.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Atorvastatin Calcium EP Impurity F is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 717.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Atorvastatin Calcium EP Impurity F (CAS 887196-24-9), a pharmacopoeial impurity reference standard (molecular formula C40H48FN3O8, MW 717.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Atorvastatin Calcium EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H48FN3O8 |
| Molecular Weight | 717.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Atorvastatin Standards
- Atorvastatin EP Impurity F (CAS 1371615-56-3)
- Atorvastatin Acyl-beta-D-glucuronide (CAS 463962-58-5)
- Atorvastatin Impurity 67 (CAS 693793-87-2)
- Atorvastatin 3-Isopropyl Ether tert-Butyl Ester (CAS 1797009-04-1)
- Atorvastatin Impurity 76 (CAS 1099474-28-8)
- Atorvastatin EP Impurity I (CAS 125971-95-1)
- Atorvastatin Impurity 24 (CAS 472967-95-6)
- Atorvastatin Impurity 66 (CAS 1105067-90-0)
Recommended Standards
- Boc-NH-PEG12-CH2CH2COOH (CAS 1415981-79-1)
- Levothyroxine EP Impurity I (CAS 2016-06-0)
- t-Boc-N-amido-PEG-acid 3000 (CAS 187848-68-6)
- Eravacycline impurity 39 (CAS CATO-C4X-293839)
- Rimegepant Impurity 105 (CAS CATO-C4X-2487105)
- Resmetirom impurity 137 (CAS CATO-C4X-2912137)
- Benzhexol Impurity 11 (CAS 161564-79-0)
- 2-methyl-N-(octahydroindolizin-1-yl)cyclopropane-1-carboxamide (CAS 1311712-10-3)
- (dicyclopropyl-4H-1,2,4-triazol-3-yl)methanol (CAS 1461707-62-9)
- (S)-(3-Amino-4-((3-hexylphenyl)amino)-4-oxobutyl)phosphonic acid (CAS 909725-63-9)
- 138084-66-9 5-Amino-2-chloropyridin-4(1H)-one DTXSID00663816 (CAS 138084-66-9)
- N-allyl-5-chloropyridin-2-amine (CAS 89981-18-0)
- 5-Ethyl-1-isopropyl-1H-pyrazole-3,4-diamine (CAS 199341-43-0)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com