Flurbiprofen impurity 121 CAS 74648-00-3
| CAS No. | 74648-00-3 |
| Molecular Formula | C15H12FN |
| Molecular Weight | 225.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 225.26 g/mol gives Flurbiprofen impurity 121 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Flurbiprofen impurity 121 (CAS 74648-00-3) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12FN and a molecular weight of 225.26 g/mol.
Based on its molecular formula C15H12FN, Flurbiprofen impurity 121 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 225.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Flurbiprofen impurity 121 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12FN |
| Molecular Weight | 225.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Flurbiprofen Standards
- Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A) (CAS 6341-72-6)
- Flurbiprofen Impurity 84 (CAS 5001-96-7)
- Flurbiprofen Impurity 173 (CAS CATO-C4X-1444173)
- Flurbiprofen Impurity 40 (CAS 92-66-0)
- Flurbiprofen Impurity 37 (CAS 56430-67-2)
- Flurbiprofen EP Impurity E (CAS 137045-30-8)
- Flurbiprofen EP Impurity D (CAS 42771-79-9)
- Flurbiprofen Impurity 68 (CAS CATO-C4X-144468)
Recommended Standards
- Levocarnitine Impurity 7 (CAS CATO-C4X-12927)
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- Nebivolol Impurity 10 (CAS CATO-C4X-196810)
- Halometasone Impurity N3 (CAS 23961-22-0)
- Levocarnitine Impurity 20 (CAS CATO-C4X-129220)
- Simvastatin EP Impurity I (CAS 79902-42-4)
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- 2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)propanamide (CAS 1251387-03-7)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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