Flurbiprofen Impurity 40 CAS 92-66-0
| CAS No. | 92-66-0 |
| Molecular Formula | C12H9Br |
| Molecular Weight | 233.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Flurbiprofen Impurity 40 is closely related to bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Flurbiprofen Impurity 40 (CAS 92-66-0, C12H9Br) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to bromine substitution, an aromatic ring system, Flurbiprofen Impurity 40 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 233.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Flurbiprofen Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9Br |
| Molecular Weight | 233.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 173 (CAS CATO-C4X-1444173)
- Flurbiprofen Impurity 84 (CAS 5001-96-7)
- Flurbiprofen Impurity 68 (CAS CATO-C4X-144468)
- Flurbiprofen Impurity 99 (CAS CATO-C4X-144499)
- Flurbiprofen Impurity 47 (CAS 1912791-27-5)
- Flurbiprofen Impurity 92 (CAS CATO-C4X-144492)
- Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A) (CAS 6341-72-6)
- Flurbiprofen impurity 121 (CAS 74648-00-3)
Recommended Standards
- 4-Bromo-2,3-dihydro-7-hydroxy-1-indanone 4-Bromo-7-hydroxy-1-indanone 81945-13-3 (CAS 81945-13-3)
- Pbb-No. 1 (CAS 2052-07-5)
- methyl 5-bromobicyclo[3.1.1]heptane-1-carboxylate (CAS 91239-76-8)
- 3-Bromobipheny (CAS 2113-57-7)
- Sunitinib Impurity 51 (CAS 253870-02-9)
- Sunitinib Impurity 48 (CAS 71294-03-6)
- Diclofenac acid Impurity 59 (CAS 304884-75-1)
- (4-Bromo-2-hydroxyphenyl)thiourea (CAS 1404480-07-4)
- Ambuic acid (CAS 340774-69-8)
- 3-bromoimidazo[1,2-a]pyridine-8-carbaldehyde (CAS 1033434-54-6)
- 2-Chloro-6-(o-tolylthio)-1H-purine (CAS 646509-48-0)
- 2-Mercaptopyrimidin-4-ol (CAS 80275-68-9)
- 2-(3,5-Dibromo-4-((2-methylquinolin-6-yl)oxy)phenoxy)acetic acid (CAS 918946-55-1)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com