Imidazo[1,5-a]pyrazine-8-thiol CAS 746547-06-8
| CAS No. | 746547-06-8 |
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Imidazo[1,5-a]pyrazine-8-thiol.
Imidazo[1,5-a]pyrazine-8-thiol (CAS 746547-06-8) is a high-purity analytical reference standard with the molecular formula C6H5N3S and a molecular weight of 151.19 g/mol.
The molecular framework of Imidazo[1,5-a]pyrazine-8-thiol (C6H5N3S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Imidazo Standards
- Imidazo[1,2-a]pyrazine-5-thiol (CAS 112266-79-2)
- Imidazo[1,2-b]pyridazine-6(5H)-thione (CAS 122322-14-9)
- 1H-Imidazo[4,5-b]pyridine-2-thiol (CAS 29448-81-5)
- Imidazo[1,2-a]pyrazine-6-thiol (CAS 763916-91-2)
- Imidazo[1,5-a]pyrazine-3(2H)-thione (CAS 56488-16-5)
- imidazo[1,2-a]pyridine-6-carbonitrile (CAS 106850-34-4)
- imidazo[1,2-a]pyridine-8-carbonitrile (CAS 136117-70-9)
- imidazo[1,2-a]pyridine-7-carbonitrile (CAS 952566-04-0)
Recommended Standards
- Isothiazolo[4,3-b]pyridin-3-ylamine (CAS 42242-13-7)
- Isothiazolo[4,5-b]pyridin-3-amine (CAS 2089325-25-5)
- benzothiazol-4-ol (CAS 7405-23-4)
- Isothiazolo[5,4-b]pyridin-3-amine (CAS 56891-64-6)
- 1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid methyl ester 351439-07-1 A822605 methyl 1H-pyrrolo[2,3-b]pyridine-4-carboxylate (CAS 351439-07-1)
- Ytterbium(III) oxide (CAS 1314-37-0)
- 4-Methyl-1-cyclohexene-1-carboxylic acid (CAS 5333-31-3)
- Perfluorodecene-1 (CAS 35328-43-9)
- 6-Bromo-4-formylpicolinonitrile (CAS 1289035-24-0)
- 4-Chloro-2-(((1-methyl-1H-benzo[d]imidazol-2-yl)amino)methyl)phenol (CAS 364742-46-1)
- 5-Bromo-3-methyl-2,3-dihydro-1H-indol-2-one (CAS 90725-49-8)
- tert-Butyl 2,4-dichloro-8-oxo-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate (CAS 1207368-89-5)
- 2-(2,6-Dimethyl-4-nitrophenoxy)acetamide (CAS 1706451-05-9)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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