Isothiazolo[5,4-b]pyridin-3-amine CAS 56891-64-6
| CAS No. | 56891-64-6 |
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isothiazolo[5,4-b]pyridin-3-amine.
CATO supplies Isothiazolo[5,4-b]pyridin-3-amine (CAS 56891-64-6), a certified reference material (molecular formula C6H5N3S, MW 151.19 g/mol) for analytical method development and quality control.
The molecular framework of Isothiazolo[5,4-b]pyridin-3-amine (C6H5N3S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Isothiazolo Standards
- Isothiazolo[4,5-c]pyridin-3-amine (CAS 1367990-09-7)
- Isothiazolo[3,4-c]pyridin-3-amine (CAS 150364-74-2)
- Isothiazolo[5,4-c]pyridin-3-amine (CAS 150364-77-5)
- Isothiazolo[4,3-b]pyridin-3-ylamine (CAS 42242-13-7)
- Isothiazolo[4,5-b]pyridin-3-amine (CAS 2089325-25-5)
- Isothiazolo[5,4-b]pyridin-3-ol (CAS 4337-60-4)
- Isothiazolo[4,5-b]pyrazin-3-amine (CAS 92914-68-6)
- Isothiazolo[5,4-d]pyrimidin-4-ol (CAS 1498711-48-0)
Recommended Standards
- Thiazolo[3,2-a]pyridin-4-ium-3-olate (CAS 42715-25-3)
- Thiazolo[4,5-c]pyridin-2-amine (CAS 89786-54-9)
- Imidazo[1,5-a]pyrazine-8-thiol (CAS 746547-06-8)
- Thiazolo[5,4-b]pyridin-6-amine (CAS 948306-28-3)
- Tert-butyl bromoacetate-2-<SUP>13</SUP>C (CAS 1173022-29-1)
- 9-(4-Aminophenyl)-9H-purin-6-amine (CAS 863675-87-0)
- 2-Phenylthieno[3,2-c]pyridin-4(5H)-one (CAS 690636-03-4)
- Mivacurium chloride Impurity 68 (CAS CATO-C4X-137568)
- 4-(Dimethylamino)-2-[(3-methylphenyl)sulfanyl]pyridine-3-carbonitrile (CAS 478262-63-4)
- N-Boc-D-Leucine Monohydrate (CAS 200937-17-3)
- 2-Fluoro-5-hydroxybenzene-1-sulfonyl chloride (CAS 1261837-43-7)
- 2-(4-Chlorophenyl)benzo[d]oxazole-5-carbaldehyde (CAS 1181377-97-8)
- methyl 3-(tert-butoxy)-2,2-dimethylpropanoate (CAS 35889-99-7)
- 149471-11-4 Neuropeptide DF2 L-Phenylalaninamide, L-alpha-aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl- Asp-arg-asn-phe-leu-arg-phe-NH2 Aspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamide L-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide DF(2) Neuropeptide Drnflrfamide (CAS 149471-11-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com