9-Chloro-6-methoxy-2-(trifluoromethyl)acridine CAS 811432-17-4
| CAS No. | 811432-17-4 |
| Molecular Formula | C15H9ClF3NO |
| Molecular Weight | 311.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine.
9-Chloro-6-methoxy-2-(trifluoromethyl)acridine (CAS 811432-17-4) is a high-purity analytical reference standard with the molecular formula C15H9ClF3NO and a molecular weight of 311.69 g/mol.
The molecular framework of 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine (C15H9ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9ClF3NO |
| Molecular Weight | 311.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline (CAS 860785-05-3)
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Recommended Standards
- 5-(3-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-02-1)
- Clodinafop (racemic) (CAS 87135-08-8)
- 5-(2-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-04-3)
- methyl (Z)-2-azido-3-[2-chloro-4-(trifluoromethyl)phenyl]prop-2-enoate (CAS 2755783-48-1)
- (1S,2S)-N,N'-Dihydroxy-N,N'-bis(3,3,3-triphenylpropionyl)cyclohexane-1,2-diamine (CAS 1217447-82-9)
- 7-Aminoquinoline Hydrochloride (CAS 1246556-01-3)
- Benzyl (3-(methylamino)-3-oxopropyl)carbamate (CAS 123494-21-3)
- 6-Fluoro-N-(3-(methylthio)propyl)pyridin-2-amine (CAS 1343329-61-2)
- N-(5-Cyclopropoxy-4-fluoropyridin-2-yl)methanesulfonamide (CAS 1243451-52-6)
- 1-Bromo-4-chloro-3-fluoro-2-(methoxymethyl)benzene (CAS 2379322-10-6)
- N-Nitroso Decyl Aminoquat (CAS CATO-C4X-28396)
- 4-Amino-2-methoxyphenyl acetate (CAS 71573-23-4)
- 1-(2-Cyclopropylethyl)cyclopropane-1-carboxylic acid (CAS 1523690-92-7)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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