Pentoxifylline EP Impurity K CAS 74857-22-0
| CAS No. | 74857-22-0 |
| Molecular Formula | C17H20N8O4 |
| Molecular Weight | 400.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pentoxifylline EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Pentoxifylline EP Impurity K (CAS 74857-22-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N8O4 and a molecular weight of 400.39 g/mol.
Structurally, Pentoxifylline EP Impurity K (C17H20N8O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 400.39 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H20N8O4 |
| Molecular Weight | 400.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 8 |
Related Pentoxifylline Standards
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- Pentoxifylline EP Impurity H (CAS 200556-62-3)
- Pentoxifylline Impurity N2 (CAS 1243654-85-4)
- Pentoxifylline Impurity 26 (CAS CATO-C4X-172826)
- Pentoxifylline Impurity N4 (CAS 84321-40-4)
- Pentoxifylline impurity 37 (CAS CATO-C4X-172837)
- Pentoxifylline Impurity 17 (CAS 1185995-26-9)
- Pentoxifylline Impurity 18 (CAS 1185878-98-1)
Recommended Standards
- Cinacalcet Impurity 75 (CAS CATO-C4X-105975)
- Fluvoxamine Impurity 14 (CAS CATO-C4X-195114)
- CAS 2591180-39-9 (CAS 2591180-39-9)
- Venetoclax Impurity 17 (CAS CATO-C4X-249517)
- Caspofungin EP Impurity A (CAS 1202167-57-4)
- Lefamulinum Impurity 29 (CAS CATO-C4X-304729)
- Salcaprozate Impurity 8 (CAS CATO-C4X-25078)
- 5-[(dimethylamino)methyl]furan-2-carboxylic acid (CAS 86649-59-4)
- (4-Chloro-3-formylthiophen-2-yl)boronic acid (CAS 36155-92-7)
- 6-Chloro-N-(4-fluorophenyl)pyridin-3-amine (CAS 509953-60-0)
- (1R,2R,4R,5R)-2,5-Bis(3,5-di-tert-butyl-2-hydroxybenzylideneamino)bicyclo[2.2.1]heptane (CAS 539834-19-0)
- (2R,3R,4R)-2-Fluoro-3,4,5-trihydroxypentanal (CAS 7226-33-7)
- pentacyclo[6.3.0.0^{2,6}.0^{3,10}.0^{5,9}]undecane-4-carboxylic acid (CAS 115044-28-5)
- Heptapeptide-6 (CAS CATO-CPTD788823)
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