Pentoxifylline EP Impurity H CAS 200556-62-3
| CAS No. | 200556-62-3 |
| Molecular Formula | C18H26N4O4 |
| Molecular Weight | 362.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 362.42 g/mol gives Pentoxifylline EP Impurity H distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Pentoxifylline EP Impurity H (CAS 200556-62-3, C18H26N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H26N4O4, Pentoxifylline EP Impurity H contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 362.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H26N4O4 |
| Molecular Weight | 362.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 4 |
Related Pentoxifylline Standards
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- Pentoxifylline Impurity N2 (CAS 1243654-85-4)
- Pentoxifylline EP Impurity K (CAS 74857-22-0)
- Pentoxifylline Impurity 26 (CAS CATO-C4X-172826)
- Pentoxifylline Impurity N4 (CAS 84321-40-4)
- Pentoxifylline impurity 37 (CAS CATO-C4X-172837)
- Pentoxifylline Impurity 17 (CAS 1185995-26-9)
- Pentoxifylline Impurity 18 (CAS 1185878-98-1)
Recommended Standards
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- Nintedanib Impurity 51 (Z-Isomer) (CAS 2102162-79-6)
- Ropinirole Impurity 3 HCl (CAS 221264-43-3)
- Lumateperone Impurity 14 (CAS 1576240-09-9)
- Captopril EP Impurity E (CAS 23500-15-4)
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- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
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