N-(4-Chloro-2-methoxyphenyl)-2-[2-(hydrazinecarbonyl)phenoxy]acetamide CAS 748776-44-5
| CAS No. | 748776-44-5 |
| Molecular Formula | C16H16ClN3O4 |
| Molecular Weight | 349.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-Chloro-2-methoxyphenyl)-2-[2-(hydrazinecarbonyl)phenoxy]acetamide (C16H16ClN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies N-(4-Chloro-2-methoxyphenyl)-2-[2-(hydrazinecarbonyl)phenoxy]acetamide (CAS 748776-44-5), a certified reference material (molecular formula C16H16ClN3O4, MW 349.77 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-Chloro-2-methoxyphenyl)-2-[2-(hydrazinecarbonyl)phenoxy]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16ClN3O4 |
| Molecular Weight | 349.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-(2-Chloro-4-formyl-6-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide (CAS 717892-23-4)
- 2-chloro-N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]propanamide (CAS 2321768-17-4)
- 3-chloro-N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]propanamide (CAS 2321768-15-2)
- n-(4-Chloro-2-methoxyphenyl)-2-(4-formyl-2-methoxyphenoxy)acetamide (CAS 748776-40-1)
- 5-[1-(4-Chloro-phenyl)-1H-tetrazol-5-yl]-4-phenyl-pyrimidin-2-ylamine (CAS 139393-52-5)
- (2E)-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2-[(dimethylamino)methylidene]-3-oxobutanenitrile (CAS 339106-44-4)
- (5Z)-5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylidene}-1,3-thiazolidine-2,4-dione (CAS 917602-19-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide (CAS 866138-14-9)
Recommended Standards
- N-(4-Chlorophenyl)-2-[2-(4-methoxyphenoxy)acetyl]-1-hydrazinecarboxamide (CAS 648915-34-8)
- Loracarbef (CAS 76470-66-1)
- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-naphthamide (CAS 921100-95-0)
- 3-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)thio)-5-methylisothiazole-4-carbonitrile (CAS 338978-36-2)
- 6-bromo-2,4-dichloro-thieno[2,3-d]pyrimidine (CAS 1784619-01-7)
- N-(tert-butyl)-3-(dimethylamino)-4-phenyl-1H-pyrazole-1-carboxamide (CAS 321553-12-2)
- tert-Butyl ((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)methyl)carbamate (CAS 1261230-15-2)
- Naloxone Impurity 20 (CAS CATO-C4X-149320)
- tert-butyl (5S)-5-ethyl-2,2-dioxo-oxathiazolidine-3-carboxylate (CAS 2476423-13-7)
- 2,3-Dichloroanisole (CAS 1984-59-4)
- ethyl 3-methylimidazo[2,1-b]thiazole-2-carboxylate (CAS 130182-29-5)
- 6-Chloro-2-(4-methoxyphenyl)-1-[(4-methylphenyl)methoxy]-1H-1,3-benzodiazole (CAS 329234-97-1)
- methyl 2-(2-bromoethoxy)benzoate (CAS 91687-70-6)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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