2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide CAS 866138-14-9

Purity 97%+In StockPharmaceutical Standards
CAS No.866138-14-9
Molecular FormulaC15H19ClF3N3O
Molecular Weight349.78 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide CAS 866138-14-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 349.78 g/mol gives 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide (CAS 866138-14-9) is a high-purity analytical reference standard with the molecular formula C15H19ClF3N3O and a molecular weight of 349.78 g/mol.

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide (C15H19ClF3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-(piperidin-1-yl)ethyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H19ClF3N3O
Molecular Weight349.78 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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