Cilnidipine Impurity 9 CAS 74936-76-8
| CAS No. | 74936-76-8 |
| Molecular Formula | C18H20N2O7 |
| Molecular Weight | 376.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Cilnidipine Impurity 9 (CAS 74936-76-8, C18H20N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Cilnidipine Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 376.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O7 |
| Molecular Weight | 376.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Cilnidipine Standards
- Cilnidipine impurity 27 (CAS 2221936-39-4)
- Cilnidipine Impurity 8 (CAS 123853-41-8)
- Cilnidipine Impurity 28 (CAS 62760-08-1)
- (E)-Cilnidipine Impurity 14 (CAS CATO-C4X-179614)
- (E)-Cilnidipine Impurity 15 (CAS CATO-C4X-179615)
- Cilnidipine impurity 22 (CAS CATO-C4X-179622)
- Cilnidipine impurity 23 (CAS 118431-66-6)
- Cilnidipine Impurity 13 (CAS 1974323-06-2)
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