Nitrendipine Impurity 5 CAS 74936-73-5
| CAS No. | 74936-73-5 |
| Molecular Formula | C17H18N2O6 |
| Molecular Weight | 346.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nitrendipine Impurity 5.
Nitrendipine Impurity 5 (CAS 74936-73-5) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18N2O6 and a molecular weight of 346.33 g/mol.
Nitrendipine Impurity 5 (C17H18N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nitrendipine Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18N2O6 |
| Molecular Weight | 346.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Nitrendipine Standards
- Nitrendipine impurity 21 (CAS 1195583-65-3)
- Nitrendipine Impurity 3 (CAS 76258-20-3)
- Nitrendipine Impurity 7 (CAS 89267-42-5)
- Nitrendipine Impurity 4 (CAS CATO-C4X-18344)
- Nitrendipine EP Impurity A (CAS 89267-41-4)
- Nitrendipine Impurity 2 (CAS CATO-C4X-18342)
- (+)-Nitrendipine (CAS 80890-07-9)
- Nitrendipine (CAS 39562-70-4)
Recommended Standards
- Rebamipide impurity 23 (CAS CATO-C4X-152323)
- Fluorescein Methyl ester (CAS 70672-06-9)
- Nifedipine Impurity 9 (CAS 21829-09-4)
- Nifedipine (CAS 21829-25-4)
- Raltitrexed Impurity 51 (CAS CATO-C4X-138651)
- Clindamycin Impurity 95 (CAS CATO-C4X-134195)
- Dronedarone Impurity 93 (CAS CATO-C4X-109293)
- 3-Bromo-2,4,6-trifluorobenzaldehyde (CAS 1160573-16-9)
- [(4-hydroxy-6-methylpyrimidin-2-yl)amino]formonitrile (CAS 7152-19-4)
- 1-[2-(dimethylamino)ethyl]-1h-indol-5-amine (CAS 462649-11-2)
- tert-Butyl N-BenzoylcarbaMate (CAS 88000-67-3)
- 4-Cyano-5-(2-cyanoacetamido)-N,N-diethyl-3-methylthiophene-2-carboxamide (CAS 581780-63-4)
- 1-(2-Chlorobenzyl)-1H-pyrrole-3-carboxylic acid (CAS 1506517-99-2)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com