Tadalafil Impurity 14 CAS 7524-52-9
| CAS No. | 7524-52-9 |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tadalafil Impurity 14 (CAS 7524-52-9), a pharmacopoeial impurity reference standard (molecular formula C12H14N2O2HCl, MW 254.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Tadalafil Impurity 14 (C12H14N2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tadalafil Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O2 HCl |
| Molecular Weight | 254.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil Impurity 10 (CAS 100077-49-4)
- Tadalafil Impurity 75 (CAS 1093940-68-1)
- Tadalafil Impurity 76 (CAS 1093940-70-5)
- Tadalafil Impurity 99 (CAS 114152-23-7)
- Tadalafil Impurity 11 HCl (CAS 1190238-20-0)
- 【禁售不询】Tadalafil Impurity 43 (CAS 120-57-0)
- Tadalafil Impurity N1 (CAS 1220393-12-3)
- Tadalafil Impurity 119 (CAS 130812-44-1)
Recommended Standards
- Itraconazole Impurity 14(and enantiomer) (CAS 67914-85-6)
- Letrozole impurity 01 (CAS 10466-37-2)
- Olmesartan Impurity 104 (CAS CATO-C4X-1097104)
- tert-Butyl N-{4-aminobicyclo[2.1.1]hexan-1-yl}carbamate (CAS 1050890-47-5)
- 1-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}-4-(pyridin-2-yl)piperazine (CAS 439096-67-0)
- 2-Fluoro-4-mercaptobenzonitrile (CAS 101187-91-1)
- 2,6-Dichloro-3-(2,6-dimethylphenyl)propiophenone (CAS 898755-37-8)
- 4-Cyclohexyloxazolidine-2,5-dione (CAS 872806-48-9)
- Isochromane-4-carboxylic acid (CAS 1261728-81-7)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com