Tocopherol Impurity 23 (Deshydroxy Tocopherol Quinone) CAS 75917-94-1
| CAS No. | 75917-94-1 |
| Molecular Formula | C29H50O2 |
| Molecular Weight | 430.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tocopherol Impurity 23 (Deshydroxy Tocopherol Quinone) (CAS 75917-94-1), a pharmacopoeial impurity reference standard (molecular formula C29H50O2, MW 430.71 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tocopherol Impurity 23 (Deshydroxy Tocopherol Quinone) (C29H50O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H50O2 |
| Molecular Weight | 430.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related Tocopherol Standards
- (2S)-α-Tocopherol (Mixture of Diastereomers) (CAS 1411583-24-8)
- (2R)-α-Tocopherol (Mixture of Diastereomers) (CAS 895518-38-4)
- Tocopherol impurity 37 (CAS 185672-33-7)
- DL-Tocopherol (CAS 2074-53-5)
- Tocopherol Impurity 25 (CAS 69371-91-1)
- Tocopherol Impurity 32 (CAS CATO-C4X-119532)
- Tocopherol Impurity 4 (CAS 3808-26-2)
- b-Tocopherol-d3(major) (CAS 936230-75-0)
Recommended Standards
- All-rac-alfa-Tocopherol EP Impurity A (Mixture of Diastereomers) (CAS CATO-C4X-119516)
- All-rac-alfa-Tocopherol EP Impurity B (Mixture of Diastereomers) (CAS CATO-C4X-119515)
- Cholesterol impurity 41 (CAS 1255-88-5)
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- 4-Chloro-7-fluoro-6-methyl-2-(trifluoromethyl)quinoline (CAS 537033-66-2)
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- N,2-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1233526-90-3)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
Why CATO?
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