2-Chloro-6-(4-chlorophenoxy)benzoic acid CAS 76093-29-3
| CAS No. | 76093-29-3 |
| Molecular Formula | C13H8Cl2O3 |
| Molecular Weight | 283.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-6-(4-chlorophenoxy)benzoic acid (C13H8Cl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Chloro-6-(4-chlorophenoxy)benzoic acid (CAS 76093-29-3), molecular formula C13H8Cl2O3 and molecular weight 283.11 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-(4-chlorophenoxy)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2O3 |
| Molecular Weight | 283.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-4-(4-chlorophenoxy)benzoic acid (CAS 1384431-04-2)
- 2-Chloro-N-(5-chloro-2-hydroxyphenyl)nicotinamide (CAS 153144-00-4)
- 2-Chloro-6-(2-chlorophenoxy)benzoic acid (CAS 76093-25-9)
- 5-Chloro-2-(3-chlorophenoxy)benzoic acid (CAS 69199-64-0)
- 5-chloro-6-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid (CAS 942511-67-3)
- 2-chloro-1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)trisilane 5565-32-2 Chlorotris(trimethylsilyl)silane (CAS 5565-32-2)
- 8-Chloro-6-fluoro-2H-chromene-3-sulfonyl chloride (CAS 1235440-07-9)
- methyl 4-chloro-5-(chlorosulfonyl)-2-methylbenzoate (CAS 102392-16-5)
Recommended Standards
- 3-[5-(2,3-Dichlorophenyl)-2-furyl]acrylic acid (CAS 463351-44-2)
- 2-{3-[(2,4-dichlorophenoxy)methyl]-1H-1,2,4-triazol-5-yl}acetonitrile (CAS 338395-57-6)
- 3-[5-(2,4-Dichlorophenyl)-2-furyl]acrylic acid (CAS 756493-00-2)
- 2-[(3,4-dichlorophenyl)amino]pyridine-3-carboxylic acid (CAS 57978-49-1)
- 4-(Benzyloxy)-2'-methyl[1,1'-biphenyl]-3-carbaldehyde (CAS 893735-20-1)
- n,3-Dimethylcyclopentan-1-amine, mixture of diastereomers (CAS 252854-33-4)
- (3AS,4R,5R,7aR)-2,2-dimethyl-3a,4,5,7a-tetrahydrobenzo[d][1,3]dioxole-4,5-diol (CAS 130669-76-0)
- 2-Acetamido-4-picoline (CAS 5327-32-2)
- 5-Amino-2-isobutyrylisoxazol-3(2H)-one (CAS 1573547-19-9)
- (S)-Methyl 2-amino-3-(4-cyanophenyl)propanoate (CAS 272784-76-6)
- tert-Butyl (4,6-dimethylpyridin-2-yl)carbamate (CAS 848472-36-6)
- 1-[(2S)-butan-2-yl]-4-chloro-1H-pyrazolo[3,4-d]pyrimidine (CAS 2382222-97-9)
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- Tirzepatide Impurity 1 (CAS 2460751-66-8)
Why CATO?
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