Promethazine Impurity 67 CAS 7647-63-4
| CAS No. | 7647-63-4 |
| Molecular Formula | C19H25N2OS |
| Molecular Weight | 329.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Promethazine Impurity 67 (CAS 7647-63-4), a pharmacopoeial impurity reference standard (molecular formula C19H25N2OS, MW 329.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H25N2OS, Promethazine Impurity 67 contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Promethazine Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H25N2OS |
| Molecular Weight | 329.48 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Promethazine Standards
- Promethazine Impurity 66 (CAS CATO-C4X-141866)
- Promethazine Impurity 47 (CAS CATO-C4X-141847)
- Promethazine Impurity 37 (CAS CATO-C4X-141837)
- Promethazine Impurity 63 (CAS CATO-C4X-141863)
- Promethazine Impurity 8 (CAS CATO-C4X-14188)
- Promethazine Impurity 62 (CAS CATO-C4X-141862)
- Promethazine Impurity 64 (CAS CATO-C4X-141864)
- Promethazine sulfoxide HCl (CAS 5306-81-0)
Recommended Standards
- Bornaprine (CAS 20448-86-6)
- Prenylamine (CAS 390-64-7)
- Androisoxazole (CAS 360-66-7)
- (2S,4aS,4bS,8S,8aS,10aS)-8-(2-Cyanoethyl)-4a-methyl-7-methylenetetradecahydrophenanthren-2-yl acetate (CAS 23498-57-9)
- Methionine EP Impurity A (CAS 3226-65-1)
- Adenosine Cyclophosphate impurity 4 (CAS CATO-C4X-31734)
- Nepafenac Impurity 1 (CAS 2835-77-0)
- 3,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine (CAS 30169-25-6)
- 2-(2,6-Dihydroxypyridin-4-yl)acetic acid (CAS 1393573-86-8)
- (5-(Methoxycarbonyl)-2-methylpyridin-3-yl)boronic acid (CAS 2225174-41-2)
- (2Z)-1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-(1H-imidazol-2-yl)-2-propen-1-one (CAS 252950-15-5)
- Cefpodoxime Impurity 60 (CAS CATO-C4X-157960)
- (1R,2R,4S)-Bicyclo[2.2.1]heptan-2-amine hydrochloride (CAS 673459-33-1)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com