Iohexol Impurity 11 CAS 76820-35-4
| CAS No. | 76820-35-4 |
| Molecular Formula | C14H21N3O6 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Iohexol Impurity 11.
CATO supplies Iohexol Impurity 11 (CAS 76820-35-4), a certified reference material (molecular formula C14H21N3O6HCl, MW 363.80 g/mol) for analytical method development and quality control.
The molecular framework of Iohexol Impurity 11 (C14H21N3O6HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Iohexol Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21N3O6 HCl |
| Molecular Weight | 363.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Iohexol Standards
- Iohexol Impurity 31 (CAS 1096689-22-3)
- Iohexol EP Impurity F (CAS 1215856-35-1)
- Iohexol Impurity N9 (CAS 122731-58-2)
- Iohexol Impurity 13 (CAS 122731-74-2)
- Iohexol EP Impurity D (CAS 157739-09-8)
- Iohexol Impurity 51 (CAS 1651211-78-7)
- Iohexol EP Impurity H (4,6-diiodo Isomer) (Mixture of Diastereomers) (CAS 1651211-79-8)
- Iohexol EP Impurity I (CAS 196309-19-0)
Recommended Standards
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- 3-(4-Bromothiophen-2-yl)acrylaldehyde (CAS 1046162-02-0)
- 117889-72-2 5-Ethyl-2-pyrimidinol hydrochloride MFCD20441447 (CAS 117889-72-2)
- 2-Amino-N,N-dimethyl-3-phenylpropanamide (CAS 3705-50-8)
- 3-((6-Methylpyridin-2-yl)oxy)quinuclidine (CAS 2199972-15-9)
- 5-Bromo-6-methylpyrazolo[1,5-a]pyridine (CAS 1345121-35-8)
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